A [1]review of 62 scientific studies published in Osteoporosis International found that microplastics weaken bones by [2]disrupting bone marrow stem cells and stimulating osteoclasts , cells that degrade bone tissue. Laboratory experiments found the particles reduce cell viability, induce premature cellular aging, modify gene expression, and trigger inflammatory responses. Animal studies found microplastic accumulation decreases white blood cell counts and deteriorates bone microstructure, creating irregular cell structures that increase fracture risk. Rodrigo Bueno de Oliveira from the State University of Campinas in Brazil said the effects interrupted skeletal growth in test animals.



[1] https://link.springer.com/article/10.1007/s00198-025-07580-4

[2] https://www.wired.com/story/microplastics-could-be-weakening-your-bones-research-suggests-osteoporosis/