Weight-Loss Surgery Down 25% as Anti-Obesity Drug Use Soars (harvard.edu)
- Reference: 0175366919
- News link: https://science.slashdot.org/story/24/10/31/1230224/weight-loss-surgery-down-25-as-anti-obesity-drug-use-soars
- Source link: https://news.harvard.edu/gazette/story/2024/10/weight-loss-surgery-down-25-percent-as-anti-obesity-drug-use-soars/
> The study, by researchers at Brigham and Women's Hospital, in collaboration with researchers at Harvard T.H. Chan School of Public Health and the Brown School of Public Health, is published in JAMA Network Open. "Our study provides one of the first national estimates of the decline in utilization of bariatric metabolic surgery among privately insured patients corresponding to the rising use of blockbuster GLP-1 RA drugs," said senior author Thomas C. Tsai, a metabolic bariatric surgeon at Brigham and Women's Hospital.
>
> Using a national sample of medical insurance claims data from more than 17 million privately insured adults, the researchers identified patients with a diagnosis of obesity without diabetes in 2022-2023. The study found a sharp increase in the share of patients who received glucagon-like peptide-1 receptor agonists, or GLP-1 RAs, during the study period, with GLP-1 RA use increasing 132.6% from the last six months of 2022 to the last six months of 2023 (from 1.89 to 4.41 patients per 1,000 patients).
>
> Meanwhile, there was a 25.6% decrease in use of bariatric metabolic surgery during the same period (from 0.22 to 0.16 patients per 1,000 patients). Among the sample of patients with obesity, 94.7% received neither form of treatment during the study period (while 5% received GLP-1 RAs and 0.3% received surgery). Compared to patients who were prescribed GLP-1 RAs, patients who underwent surgery tended to be more medically complex.
[1] https://news.harvard.edu/gazette/story/2024/10/weight-loss-surgery-down-25-percent-as-anti-obesity-drug-use-soars/
Final nail in coffin for "broken metabolism" ppl (Score:1, Insightful)
We've been hearing all the time how it's "not their fault", "they're not overeating it's just their broken thyroid/liver/pancreas/whatever that's making them fat". The fabled "broken metabolism" people who say they're eating 1200 calories and STILL gain weight.
Well guess what. Pharma companies have spent literal, actual billions looking for the "broken metabolism" drug. You know how all those studies went? The search for the "broken metabolism" people? They recruited all those "broken metabolism" ladies
Re: (Score:2, Informative)
"Ozempic does exactly NOTHING to your metabolism. It is, however, a powerful appetite suppressant. That's all."
All of this is wrong and you're a moron, if that's not already obvious to everyone after the stupid shit you just spewed.
"Eating less makes you loose weight. Who would have thought."
Everyone would have thought, and already did. The problem lies elsewhere, but you wouldn't know that because you've never experienced the problems others do.
Re: (Score:3)
More than 2/3rds of Americans are overweight or obese, so while you might be correct that someone with enough willpower can lose weight, the reality today in that society is that most of them can't.
It's not like you haven't been berating them for decades either, so it's not like just listening to you is going to help. Where people have been forced to stick to 1200 calories, be it in controlled studies or on TV shows, while it does work in the short term they almost always put the weight back on. And that in
Re:Final nail in coffin for "broken metabolism" pp (Score:5, Insightful)
In addition to being addicted to junk food, Americans are also addicted to treating large scale social issues as individual moral failure.
Re: (Score:1)
People are also somewhat resistant to the "nanny state" telling them what to do, protecting them from predatory businesses, or even giving them useful information like how many calories are in a particular item.
Re: (Score:2)
> or even giving them useful information like how many calories are in a particular item.
Okay, the US isn't perfect, but we definitely do this one.
Re: (Score:1)
Nobody's addicted to junk food. We work more fucking hours than the Japanese. We junk food because real healthy food takes a lot of time to prepare.
I know because I cook all my own meals. I spend about 3 hours a week putzing around grocery stores to get all the ingredients then I've got to get them home and put them away in my tiny ass little apartment fridge which requires a game of Tetris at the end of every trip. Then I've got to clean and prep the vegetables heat up all the pans on a crappy apartment
I don't think it's a question of willpower (Score:1)
If you combine long hours with high stress and cheap easily prepared high calorie junk food and then you add in all sorts of things that are killing the gut bacteria that would give us the metabolisms needed to deal with all that then yeah you're going to have problems.
Every time there's an ozempic story it's guaranteed to show up on here but I don't see nearly as many stories about the effects of plastic in our food supply. I do get stories every time some little town tries to ban disposable grocery ba
Re: (Score:2)
> Eating less makes you loose weight. Who would have thought.
Current understanding of how metabolic regulation makes this false on its face. Your body has a calorie consumption set point. If you ignore the signals and simply eat below the set point, your body will attempt to conserve energy in various ways. This includes moving less – you will subconsciously fidget less and become lazier generally, and cutting brain activity – you will literally think worse and become more sleepy and sluggish.
It is incredibly hard to beat biology once your body has reac
Re: (Score:2)
It's difficult to take seriously someone who can't spell "lose."
> Ozempic does exactly NOTHING to your metabolism.
>> You're aware that Ozempic is a diabetes drug right? You might want to actually use this miracle of the modern world, which you're using to post shit, for its intended purpose, and Google why Ozempic is a diabetes drug.
Most people get no treatment (Score:2)
“Metabolic bariatric surgery and GLP-1 RAs are both effective interventions for patients with obesity, yet less than 6 percent of patients in our study received either form of treatment.”
Understandable in a way. The drugs are expensive and can have serious side effects. The average cost of bariatric surgery ranges between $17,000 and $26,000, but it reportedly is relatively safe and often results in significant weight loss.
[1]https://www.saintalphonsus.org... [saintalphonsus.org]
[1] https://www.saintalphonsus.org/services/surgery/metabolic-and-bariatric-surgery
Re: (Score:1)
"...and often results in significant weight loss" True, but they weight can come back over time.
There are people who need this BUT... (Score:1)
There are certainly people in this world who need help loosing weight with things like these weight loss drugs but the fact that obesity has grown by such magnitudes in the last half century shows that for an awful lot of people it's bad lifestyle choices causing their problems. A lot of people will likely end up having to deal with unpleasant side effects from these drugs because they couldnt get their own lives in order and instead chose pharmaceuticals over self discipline to resolve years of bad decisio
Re: (Score:3)
> ... the fact that obesity has grown by such magnitudes in the last half century shows that for an awful lot of people it's bad lifestyle choices causing their problems.
Hard disagree. Changes of that degree are rarely due to individual choices. What this really shows is that our society as a whole (led by those looking to make a buck) has made an awful lot of bad lifestyle choices, starting with building ourselves into a car-dependent culture.
Re: (Score:2)
> Hard disagree. Changes of that degree are rarely due to individual choices.
Every person who sees their belly expanding and chooses to not make lifestyle changes to counter that effect is making an individual choice.
Obesity is another form of mental illness (Score:2, Insightful)
When you're eating enough to be fat enough it is having a serious negative effect on your life and you're not willing to reduce your food intake... That's a mental issue. A behavior you can't manage to change.
Drugs and surgery are temporary corrections of the symptom, if you don't deal with the problem - wanting and consuming too much food - you're going to need more drugs or surgery, or you're going to get fat again.
Re:Obesity is another form of mental illness (Score:4, Insightful)
Over 2/3rds of Americans are overweight or obese. That seems to rule out mental problems, because what is a normal mental state is defined by the behaviour of the majority. Few people believe in little green men so that's a delusion, but a lot of people believe an omnipotent being controls their life and responds to flattery, so that's perfectly normal.
Would you also say that people who are addicted to tobacco products also have a "mental issue"? It's not an unreasonable comparison. Food companies are strongly motivated to create products that are addictive, and then use every means they can to induce you to buy them.
Re: (Score:2)
If you have the capacity to change your behavior and you're suffering because you won't... It's a mental issue no matter how common it is. This can be heavily influenced by your environment and culture, but the truth is that if you WANT to be healthier, it's not impossible to do so without and easy/quick fix solution. You can even eat healthier in addition to eating less, and save money while doing so.
It takes some effort. Culturally, we're not that big on effort. Most people pretend - taking up a new
Re: (Score:2)
Consider that these medications are not cheap, and a hefty chunk of change every week is a pretty big motivator. Between that, the people fat shaming them, the desire to look conventionally attractive, the health problems obesity causes, the daily inconveniences, the rising cost of food, you would have to assume that the majority of Americans are extremely lazy and willing to put up with a hell of a lot just to avoid your easy and effective solution.
A more likely explanation is that it is in fact far harder
Re: (Score:2)
> the people fat shaming them
I'd never do that. I consider it more or less a choice they've made. As long as they don't demand that I find them attractive or pretend that it's healthy, it's generally none of my business.
> it is in fact far harder than you realize.
I've lost weight. And gained. And lost. Not on a huge scale, but I have been heavy enough my doctor told me I should be quite a bit lighter. I'm still slightly above where I should be, but I know when my weight is going to fluctuate signi
Re: (Score:2)
> That seems to rule out mental problems, because what is a normal mental state is defined by the behaviour of the majority.
Does it? The number of obese Americans has tripled in the last 60 years [1]https://usafacts.org/articles/... [usafacts.org] which pretty much means there's a mental issue at some level here for a lot of people regardless of whatever "normal" is. Everyone knows eating lots of sweet treats will put pounds on, everyone knows fast food will too. The choice to continue heavily consuming such items despite being able to physically see the negative effects on one's health (the expanding belly) is a mental one.
And sure, things like
[1] https://usafacts.org/articles/obesity-rate-nearly-triples-united-states-over-last-50-years/
Re: (Score:2)
So your theory is that more than 2/3rds of Americans have developed mental problems, as opposed to the far more likely hypothesis that foods and eating habits have changed dramatically over the last 60 years?
Re: (Score:2)
No, my theory is that roughly a third of Americans are making bad decisions in regards to their health. Obesity and being overweight has been a thing since well before the current epidemic of it and as I eluded to before those with such predispositions have my sympathies and should consider these drugs as many of them have needs that go beyond what diet and exercise can accomplish. Never the less, there's about a third of the population that clearly just arent taking responsibility for their actions given h
Re:Obesity is another form of mental illness (Score:4, Insightful)
> Would you also say that people who are addicted to tobacco products also have a "mental issue"? It's not an unreasonable comparison. Food companies are strongly motivated to create products that are addictive, and then use every means they can to induce you to buy them.
When my overweight wife would get hungry, she had exactly the same symptoms as when I would be in withdrawal from nicotine.
Re: (Score:2)
I heard the same thing from a friend, and I'm ashamed to say I didn't believe them at the time.
Re:Obesity is another form of mental illness (Score:5, Insightful)
"Mental problems," no, but knowledge lack, yes. YES I'm 25 pounds overweight so I'm not on my high horse - but what I see in terms of food with minimal nutrition in people's shopping carts is astounding. OF COURSE people eat too much - they are fat, but starving, because they aren't getting enough nutrition.
Re:Obesity is another form of mental illness (Score:4, Interesting)
I dunno about you, but I eat a lot of real food--things that used to be plants and animals. I'm grateful to be in a position to be able to do that. So would I reduce my food intake without altering my appetite? Maybe someone that eats like crap could say "one fewer bag of crisps per day", but what would I say? One less spoon of chicken and black beans? 25% less olive oil in the hummus? Eat smaller fruit? Unless your food comes from cans and boxes, you can't just eat less. You can do something more nuanced, like alter your appetite, learn to detect fullness earlier, or be hungrier.
> When you're eating enough to be fat enough it is having a serious negative effect on your life and you're not willing to reduce your food intake... That's a mental issue.
Food for thought: if you eat 1% too much, you will gain over two pounds per year.
No not really (Score:1)
There are a wide range of physiological reasons why people become obese. I've been packing on some pounds because of back problems making it hard to do the sort of exercise I used to do to keep fit. Also most simply when you gain weight your body creates more cells to store fat but when you lose the weight you don't lose those cells they just get smaller. Basically if you've gotten fat once it's permanently harder to keep the weight off.
This is before we get into all the gut bacteria problems many of wh
Obesity Drugs = I lack responsibility * (Score:3, Insightful)
* Not everyone does, there is a population that does need real medical intervention, and aren't just lazy, and unwilling to change, this is NOT about that group.
Okay, how many people are on these drugs, but take no real responsibility? I can name a handful of people, all women, who are on Ozempic, who DO NOT NEED IT. What do I mean, when I say they don't need it? All the people I'm thinking of have the same few points in common:
1. They have terrible diets.
2. They've all tried the fad diets, including Keto (which is for intractable epilepsy in kids, who "normal" meds don't work for).
3. They're very stationary, and their active outputs aren't useful.
4. This is important, they don't take responsibility!
Fad dieting, is NOT a method for weight loss, if you move between Keto (which you should NEVER do), Fasting (starvation), FOD MAP (which is nonsense on overdrive), and all the others, you're asking for your body to react negatively. If you eat pasta 4x a week, you're not going to lose weight. If you mix random shakes full of nuts, powders, and fruits, chances are, you're not going to lose weight because, you don't really know what's in the mess you're drinking. Stabilize your diet, so your body knows what to expect, look at what people eat who have low-fat levels, body builders and strongmen. Notice how they share the same diet, protein + simple carbs, and then just copy it adjusting for your body weight.
Once you have a real diet, that is balanced, then get to the gym, and or get active! You need to be moving, so move weights around, have some cardio, and make sure you're meaningfully and usefully active. If you sit at a desk for 8 hours a day, 5 days a week, you can't be shocked when you put on the pounds, so honestly, get a standing / sitting desk, get a little treadmill and walk while you work. Also, go to the gym, 3x a week, and try to get into some sports if you can, which can be substituted for the gym.
If you're done those things for a year or two, and you're still gaining weight, then you might actually have a problem, but, doctors today are prescribing Ozempic because after trying Keto 4 times, and FOD MAP for 1 week, after sitting on your ass for 80 hours, you had a cry session that you're a cow, and it's not your fault your fat, it's societies. All the people I'm thinking of, could get active, get a better diet, and stop making excuses, and they would be in better overall health for it. They would ALL get mad at me for saying this, while also trying to eat 10kg of pasta for dinner, covered in thick sugary sauce, with a side salad covered in equal amount of sugar dressing, then insisting I'm not a woman, so I can't understand, then laying down because "Oh, I just don't feel well."
Re: (Score:3)
Human beings evolved when the food supply was unreliable. Plants and animals had not been bread to be larger and higher in fat, or pumped full of hormones.
Modern foods are produced by people who have a vested interested in selling you as many calories as possible. The US, where this problem is the worst, also has very low food standards compared to other developed nations. Life now doesn't give people much time to prepare or even seek out healthy food.
It's not the case that people today lack the willpower a
Re: (Score:3)
That's why you need to stabilize the diet because if you don't fix that first, unless you're genetically lucky, it won't matter. Farmers markets are a great way to find high-quality meat, or, find a local meat distribution company. For the people I'm using as my base, all of them have high-quality meats available. One of them lives within 200 meters of a butcher, in a large city, the others live within a few KM from a butcher, but also near multiple open air food markets during the spring / summer, and ne
Re: (Score:2)
Around here meat is quite expensive relative to other foods, and farmers markets and butchers tend to be higher priced than supermarkets.
Pasta is cheap and very easy to prepare.
Re: (Score:2)
I live in Canada, relevant for the medical notes.
Yes, it's cheap, and easy, but you can't consume crap, and then at the same time whine about your inability to control your weight. The people I'm referring to are all well off, so groceries are not a burden, but, on the other hand, I know someone whose has a burden paying for the basics. He actually has a legit medical reason to need something like Ozempic, but on some sad notes:
1. Can't afford it (our family offered to cover it for him).
2. Can't get
Asthma inhalers = lack of responsibility (Score:1)
I mean if you were responsible you just wear a gas mask so that you didn't breathe in all the particulate or you would move to the country so you won't breathing in all the little bits of tire spat out into the air by all the cars.
What you definitely shouldn't do is consider what the combination of large amounts of gut bacteria destroying plastic and long work hours coupled with cheap junk food that requires a little or no preparation would do to a population.
Because as we all know there are no suc
Re: (Score:2)
Actually, you made a good point, I put an asterisk in because it's important to note some people have a real need. Imagine if you smoked a pack of cigarettes a day for 40 years, and then complained when you got lung cancer. Well, it's not like you didn't see it coming, you knew the risks, you accepted the risks, and the risks materialized.
On the other hand, someone could live a health lifestyle, never smoke a day in their life, and still get lung cancer, the difference is the second person has every ri
Statistically, obesity is... (Score:3)
...less curable than cancer.
Most people who lose weight with dieting gain it all back and more.
Some believe it's simple and insult those who fail to achieve healthy weight.
It's not simple!
Weight loss surgery is a crude and awful approach. The new drugs are a tiny bit better, but still are not the solution. This is a hard problem. We need research, not hate and insults
I lost 110lbs on Mounjaro (Zepbound) Last Year (Score:2)
This is a miracle drug. Not only did I lose 110lbs last year, my blood work is all back in the normal for the first time in 20 years. I eat entirely better with an eye towards nutrition. I also quit drinking (addiction breaking is a very common theme in the Tirzepatide groups) ....go figure.
I was over weight for 20 years (classic yo-yo dieter. I could lose, but it always came back. I put on 40lbs during the two years I ran marathons)
What is really cool? I turned 12 people on to the same drug. Combined we
Re: (Score:1)
Mounjaro totally reversed my wife's insulin resistance. Her blood sugar doesn't crash when she misses a meal.
Poor messaging (Score:2)
I'm not saying that these medications don't have a place, particularly for folks in extreme cases you need a jump start, but the idea that one would have to take these medications for the rest of their lives is awful. I think the part that's missing from the "balanced diet and exercise" message is that it is definitely not a "get thin quick" plan. Healthy weight loss is between 0.5-1lb per week. That means following those "balanced" routines takes a lot of time, and killing yourself in the gym for two we
Overrated (Score:1)
If you don't want to pay a grand a month, all it does is mimic a hormone that tells your brain you're full. If you want to release the real one, slam 16 oz of water every morning, take a dietary fiber pill, and take a multivitamin regularly. You will suddenly not find yourself constantly hungry unless there's something weirder going on.
Long term effects of Semaglutide (Score:2)
Long term effects of Semaglutide: Allergic Reactions, Depression and anxiety, Gastrointestinal Issues, Hypoglycemia, Kidney Issues, Pancreatitis, Thyroid Tumors
Re: (Score:2)
so it begins
we've had the fat shamers, now they will transition to being ozempic shamers because you are just miserable fucks who hate everyone because you hate yourselves. find a new easy target i guess eh
Re: (Score:1, Flamebait)
Sure, he could have sugar-coated it a little but the fact is that weight management is a matter of simple maths. What you eat minus what you burn. Unless you eat less or exercise more, or both, you won't get anywhere with weight-management in the long-term. All you'll do is make yourself addicted, dependent on expensive weight loss shots to make you feel a little bit better.
Re: (Score:3)
For people that need to lose a little weight*, calorie counting is a myth--in the sense that nobody can count the calories in their food with a high degree of accuracy, unless they subsist on stuff that came out of factories and doesn't belong in their body anyway.
Everybody* actually just relies on their appetites to tell them how much to eat. If I wake up hungry in the night, that's my appetite giving me a stern correction. If I wake up hungry in the morning, my appetite is telling me I did a good job. If
Re: (Score:1)
There was a study done in Germany that had people press a button on their phones every time they ate badly. They found that there is really no such thing as "self control". People who went to more kids birthday parties were likely to eat more cake. People who only hang around with athletes or have no friends were more likely to eat only healthy food. Hardly anyone travels in circles where eating snacks is normal would avoid eating snacks themselves. In other words, it is all about external factors.
Re: (Score:3)
True, and weight loss surgery more or less provides feedback when your stomach is full, at a smaller size.
Ozempic and its friends (I was calling it 'liquid gastric bypass' 7 years ago, essentially does the same thing by slowing the process of emptying the stomach. Which also is why the acid reflux happens.
Calorie counting is essentially useless. Adjust the foods you eat and activity level to suit, but counting calories is not how to do it. There are ocnfounding factors that throw the count off anyway. L
Re: (Score:1)
It's more than just what you eat - in some people there are biological mechanisms that aren't functioning correctly, such as the hormones that direct whether or not the body should store glucose as fat or consume it or even convert fat for the body to use. In some people, all calories are stored as fat regardless of how little they eat. and then there are hormones that tell the brain to eat less because the body has lots of fat reserves and new food intake isn't required.
drugs such as this are aimed at he
Re: (Score:1)
If we were machines it would be simple, but we are not.
It has taken me so long to start losing weight because I was taught the wrong things in school, like the old food pyramid that was very carb heavy, didn't dive into refined grains vs whole grain etc.
Even with discipline and daily visits to the gym, I could just not get the weight down. Through trial and error, Searching so much information, I finally learned how to get the right amount of protein, fiber and not refined carbs, avoid sugar that boosts hun
Re: (Score:2)
In an otherwise healthy person with normal endocrine function and appropriate muscle mass - sure calories vs calories out, is going to be the driver.
However you have people that:
1) Have far less than normal muscle mass, which means they will NOT have normal metabolism no matter what. That might not be just because the are a couch potato, could well be the result of other disease or debilitating injury. Weight control from them should be part of treatment.
2) Abnormal endocrine function is a thing, sure type-
Re: (Score:1)
Yes, people have (often self-induced) problems, but that doesn't invalidate the equation that < excess energy in means < excess energy stored. That's true in any system, not just humans but ANY system that can consume and store energy, it's basic physics. If you put too much gas in your car, the extra fuel must go somewhere, our body being evolved for having periods of plenty and periods of shortage stores it rather efficiently. So however YOU want to manage the fact we don't have shortages anymore al
Re: (Score:2)
> Sure, he could have sugar-coated it a little but the fact is that weight management is a matter of simple maths.
And drug addiction is just a simple matter of "stop taking the drugs", right?
If if was that easy, there'd be no fat people. You completely discount the power of cravings that the brain constantly bombards fat people with. In some cases it's quite literally like drug withdrawals where people are desperately Jonesing for that food. Their brain rewards them for eating more and encourages deception and self-delusion. You can draw a direct line between the junkie telling himself "I'll be fine; one more hit and I
Re: How about (Score:1, Interesting)
Itâ(TM)s not fat shaming.
You fat disgusting fucks are clogging up the entire medical industry, and forcing everyone else to pay for it.
Instead of weight loss drugs, how about you all have more heart attacks and bury yourselves faster?
Re: (Score:2)
How's the world look from up on that high horse?
Re: (Score:2)
As someone who's had weight loss surgery after a lifetime of being overweight, it's not nearly as simple as "moving your ass and not eating like a pig".
And weight loss surgery isn't a magic bullet, at all. I'd argue that in a lot of ways it is way harder than doing a traditional diet and exercise (Which you'll need to do anyways for the surgery to be a success). After a bypass you're going to face a lifetime of potential malnutrition, not being able to properly absorb nutrients and minerals, weird shit like
Re: (Score:1)
Many people get the surgery, lose some weight and then add it all back on. Hope you have good results, but a good result is solely up to you eating better and/or exercising. The surgery is just to solve the fact you have become too fat to do the exercise, not that diet wouldn't have helped (if you don't have the willpower someone has to forcibly remove your food supply), but it may not have been fast or convenient enough.