UK Unveils Plan To Cut Animal Testing Through Greater Use of AI (theguardian.com)
- Reference: 0180049368
- News link: https://news.slashdot.org/story/25/11/11/1854230/uk-unveils-plan-to-cut-animal-testing-through-greater-use-of-ai
- Source link: https://www.theguardian.com/science/2025/nov/11/uk-plan-to-cut-animal-testing-artificial-intelligence-ai-3d-bioprinting
> The roadmap unveiled by the science minister, Patrick Vallance, backs replacing certain animal tests that are still used where necessary to determine the safety of products such as life-saving vaccines and the impact pesticides have on living beings and the environment. The strategy says phasing out the use of animals in science can only happen when reliable and effective alternative methods with the same level of safety for human exposure can replace them.
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> The government said new funding for researchers and streamlined regulation would help develop methods such as organ-on-a-chip systems -- tiny devices that mimic how human organs work using real human cells. Greater use of AI to analyse vast amounts of data about molecules and predict whether new medicines will be safe and work well on humans would be deployed, while 3D bioprinted tissues could create realistic human tissue samples, from skin to liver, for testing.
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> Other plans under the strategy include an end to regulatory testing on animals to assess the potential for skin and eye irritation and skin sensitisation by the end of 2026. By 2027, researchers are expected under the strategy to end tests of the strength of botox on mice, while by 2030 pharmacokinetic studies -- which track how a drug moves through the body over time -- on dogs and non-human primates will be reduced.
[1] https://www.theguardian.com/science/2025/nov/11/uk-plan-to-cut-animal-testing-artificial-intelligence-ai-3d-bioprinting
Realistic vs real (Score:2)
The devil's always in the details, and biology has the level of detail and interactions that we have not even scratched the surface of. Cruel as it may be, animal testing is intended to give us a chance to test on a real system in order to uncover all the edge cases we can't predict or even imagine from dry data. Are those synthetic tissues and incomplete data models going to be enough to give us certainty that no one would be harmed, short or long term, when the same treatment is applied to humans? In the
Re: (Score:1)
The problem is for every hundred "We've found a cure for disease X in mice!" stories I see, I see one where the cure that worked in mice didn't not work in humans. And it may not actually work very well because humans and mice are so different.
Re: Realistic vs real (Score:2)
It's as close to a production environment as we can get, I'm afraid.
Alternatives. (Score:2)
In-Vitro and microphysiological methods and well as in-silico and biofabrication in other words, [1]NAMS. [nature.com]
[1] https://www.nature.com/articles/d41586-025-03344-6