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Exposure To Some Common Pfas Changes Gene Activity, New Study Finds (theguardian.com)

(Friday August 15, 2025 @05:21PM (msmash) from the more-you-know dept.)


New research suggests exposure to some common Pfas or "forever chemical" compounds [1]causes changes to gene activity , and those changes are linked to health problems including multiple cancers, neurological disorders and autoimmune disease. From a report:

> The [2]findings are a major step toward determining the mechanism by which the chemicals cause disease and could help doctors identify, detect and treat health problems for those exposed to Pfas before the issues advance. The research may also point toward other diseases potentially caused by Pfas that have not yet been identified, the authors said.

>

> The study is among the first to examine how Pfas chemicals impact gene activity, called epigenetics. "This gives us a hint as to which genes and which Pfas might be important," said Melissa Furlong, a University of Arizona College of Public Health Pfas researcher and study lead author.



[1] https://www.theguardian.com/environment/2025/aug/15/forever-chemicals-pfas-exposure-gene-activity

[2] https://www.sciencedirect.com/science/article/pii/S0013935125010175



Too High a Price for Benefits (Score:2)

by BrendaEM ( 871664 )

Forever lingering is bad attribute for a cancer-causing substance. [1]https://en.wikipedia.org/wiki/... [wikipedia.org]

[1] https://en.wikipedia.org/wiki/PFAS

I don't think it matters anymore (Score:2)

by rsilvergun ( 571051 )

I don't think there's enough democracy left in the world to do anything about this. There's certainly aren't enough people who aren't busy panicking over every little moral thing out there.

We have solid polling that indicates Trump won the election due to panic over trans kids in sports and healthcare for trans kids. Specifically the discredited nonsense called rapid onset gender dysphoria and the belief that your kid might just turn trans someday because of something they saw on TV...

That's just on

Re: (Score:2)

by jacks smirking reven ( 909048 )

How are we to take RFK's opinions on plastics against the White House's [1]National Strategy To End the Use of Paper Straws [whitehouse.gov]. What would the politicization of everything be without having to make drinking straws a matter of political ideology.

The fact that sentence and document exists should be looked at when we found lead in the Roman's drinking water. "Damn, they sure fucked themselves up"

[1] https://www.whitehouse.gov/wp-content/uploads/2025/04/National-Strategy-to-End-the-Forced-Use-of-Paper-Straws.4.10.pdf

Can we get a source that isn't The Guardian? (Score:2, Troll)

by sabbede ( 2678435 )

If the first thing a site does when you open it is talk about having to fight Elon Musk (?!), it isn't worth going any further. The Guardian is a garbage propaganda outlet and everything they publish must be suspect as a result.

Oh, they are also funded by billionaires, despite their claims. Bill Gates has given them millions, and he isn't the only one. They need it, they're hemorrhaging money.

Re: (Score:2)

by jacks smirking reven ( 909048 )

What do you consider reputable sources of journalism?

Re: (Score:1)

by smooth wombat ( 796938 )

The Guardian is a reputable source of journalism. The OP is just whining. You'll note they didn't criticize the content, only the source. That is standard tactic nowadays.

That said, they probably consider NewsMax or Breitbart as the epitome of "reputable" sources.

Re: (Score:2)

by HiThere ( 15173 )

Which "The Guardian"? Certainly the one I kept getting in my mailbox was NOT reputable journalism. Perhaps "The Manchester Guardian" is reputable. But I've never seen a copy. And if the US edition of "The Guardian" (without adjectival mods) is the same company as the British edition, then neither one is trustworthy, as they just say what they think will sell. And they occasionally directly contradict each other.

Re: (Score:2)

by HiThere ( 15173 )

Claiming that it's important to tight Elon Musk is not a sign that the results are untrustworthy, but it may well be taking as being extremely partisan. OTOH, anyone who trusts Musk is as intelligent as someone who trusts Zuckerberg.

I am not sure what this proves (Score:2)

by Retired Chemist ( 5039029 )

I am not suggesting that Poly fluoroalkanes are not a problem in the environment, but I am not sure what this study proves. Lots of chemicals including ones in nature effect gene activity. Aside from everything else, it is an important part of how biochemistry functions in living organisms. I think if you took any class of compounds, you would find some affected gene activity. Separating out the effects of one class of chemicals from all the others (and their interactions) is going to be very difficult.

Re: (Score:2)

by ceoyoyo ( 59147 )

It's been well known for quite a while that some fluoroalkanes cause disease. Not in the "oh, you might get cancer in forty years" way but in the "lots of cows are dying mysteriously" way. Studying the effects of those chemicals on biological systems, including genetic expression, can tell us a lot about what they're doing and potentially ways to treat those diseases.

If you steal from one author it's plagiarism; if you steal from
many it's research.
-- Wilson Mizner