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Exercise May Be the 'Most Potent Medical Intervention Ever Known' (pbs.org)

(Thursday January 02, 2025 @05:00AM (msmash) from the PSA dept.)


Exercise is the most potent medical intervention known, according to Stanford University researchers who [1]mapped its molecular effects across body tissues . In a study examining sedentary and exercising rats over eight weeks, scientists found comprehensive changes in every tissue examined, from fat cells to mitochondria, with exercise often reversing disease-related molecular changes. The findings explain how exercise reduces heart disease and cancer risks by 50%.



[1] https://www.pbs.org/newshour/show/how-exercise-may-be-the-most-potent-medical-intervention-ever-known



Yes (Score:2)

by Anonymous Coward

Exercise and eat a healthy diet.

Re: (Score:2)

by fahrbot-bot ( 874524 )

> Exercise and eat a healthy diet.

Yup. That's how the President-elect does it, and he's 78. :-)

msmash cares (Score:2)

by YetAnotherDrew ( 664604 )

msmash rings in the New Year with health non-advice. That's news for nerds, folks! That's what matters.

Re: (Score:1)

by Anonymous Coward

"Ancient texts unlocked by AI tell us that Exercise May Be the Most Potent Medical Intervention Ever Known" should have been the correct summary title IMHO.

Is that... (Score:1)

by Rukasu ( 219436 )

...what you think TFA says? Or that the submitter says? Or that the editor says?

It's no joke. (Score:5, Informative)

by Vegan Cyclist ( 1650427 )

Our bodies have evolved to move quite a lot.

Should be a 'no shit' moment, but anyone who's trained fairly seriously at an athletic activity knows just how different you feel being fit and unfit.

If you haven't - give it a go. Do something that gets your heart rate up regularly. You won't regret it.

Re: (Score:2)

by Valgrus Thunderaxe ( 8769977 )

At one point, we were evolved enough to hunt gazelles with spears, and very successfully. Very few humans have maintained this level of evolution.

Re: It's no joke. (Score:2)

by Gavino ( 560149 )

Does jerking off count?

Re: (Score:2)

by dargaud ( 518470 )

A little bit, but the best sports are those where everything in the body moves. So try sex (with an athletic partner) instead.

Re: (Score:2)

by MrKaos ( 858439 )

> Should be a 'no shit' moment, but anyone who's trained fairly seriously at an athletic activity knows just how different you feel being fit and unfit.

Everything feels better, except when you're injured and you can't work out and then it feels weird, like you missed a shower. Then again, it's probably me that's weird because I've really like working out since I was a teen.

I love field sports like hockey, footy and soccer but I'm too old now to risk the ballistic contact and stick to martial arts and weights. There is also the social aspect which a doctor tells me is good for the brain and preventing dementia. Also after lots of sports a good physio (

Link to actual research? (Score:2)

by BeaverCleaver ( 673164 )

I'm not disputing their findings, but is there an actual research paper or something we can read? What "molecular effects" did the group study? What was the magnitude of these effects? Which molecular markers did they study that *didn't* show an effect?

Re: (Score:2)

by wherrera ( 235520 )

Short answer, numerous studies support what is said by OP. Here is just one from recent (this year) medRxiv listings (there are dozens there if you search): [1]https://www.medrxiv.org/conten... [medrxiv.org]

[1] https://www.medrxiv.org/content/10.1101/2024.09.19.24313875v1.full

Re: (Score:2)

by fahrbot-bot ( 874524 )

> ... is there an actual research paper or something we can read?

He posted on /. ... :-)

[Ya know, the TFS/A are just too short; I need TFRP.]

Nothing new (Score:2)

by martin-boundary ( 547041 )

You know, this connection was already well known in the 80s! That's why I always used to watch that nice Jane Fonda on TV doing them air-obics!

Re: (Score:1)

by Lord Kano ( 13027 )

We have known this for quite some time. That's how Jack LaLanne was able to perform ridiculous feats of strength and endurance well into his 70s. He even claimed that he and his wife maintained an active sex life into his 90s.

Joe Weider lived into his 90s as well with comparatively good health compared to his contemporaries who didn't exercise like he did.

We have had this knowledge for decades but the counter-argument could be that correlation isn't causation. This kind of research is needed to prove that i

link to research (Score:3)

by SlashTex ( 10502574 )

the paper [1]https://journals.physiology.or... [physiology.org]

Charting the Molecular Terrain of Exercise: The Power of Multi-Omic Mapping

Physical activity plays a fundamental role in human health and disease. Exercise has been shown to improve a wide variety of disease states, and the scientific community is committed to understanding the precise molecular mechanisms that underlie the exquisite benefits. This review provides an overview of molecular responses to acute exercise and chronic training, particularly energy mobilization and generation, structural adaptation, inflammation, and immune regulation. Further it offers a detailed discussion on known molecular signals and systemic regulators activated during various forms of exercise and their role in orchestrating health benefits. Critically, the increasing use of multi-omic technologies is explored with an emphasis on how multi-omic and multi-tissue studies contribute to a more profound understanding of exercise biology. These data inform anticipated future advancement in the field and highlight the prospect of integrating exercise with pharmacology for personalized disease prevention and treatment.

[1] https://journals.physiology.org/doi/abs/10.1152/physiol.00024.2024

Well, duh (Score:2)

by bradley13 ( 1118935 )

Sure, it's nice to investigate the metabolic effects of exercise. However, the headline is stupidly obvious. This has been common knowledge for literally thousands of years. Hippocrates in Ancient Greece wrote "Eating alone will not keep a man well; he must also take exercise. For food and exercise, while possessing opposite qualities, yet work together to produce health."

Architectural Indigestion:
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architectural environment. Frequently related objects of fetish
include framed black-and-white art photography (Diane Arbus a
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